Executive Advisory Group

Sir Alex Markham – Chair

Professor Sir Alex Markham is Director of Research and Professor of Medicine at Leeds University. At the PMC, Sir Alex will lead the Expert Advisory Board which will bring a range of voices and perspectives into the organisation to guide its work. These will include charities and patient groups, as well as academics and industry leaders.

Sir Alex has made contributions to medical science in various fields. He trained initially in medicinal chemistry and is also accredited in pathology and internal medicine. His work has included the development of DNA Fingerprinting, which received the Queen’s Award for Technological Achievement in 1990, as well as cancer drug development.

Now at Leeds University, Sir Alex will help forge strong bonds with the PMC Centre of Excellence in the city and across the Northern Powerhouse. He is also a member of the Board of the Medicines Discovery Catapult, based at Alderley Park in Cheshire, which began its work in April 2016.

Dr Jonathan Sheffield OBE – Office of the CEO – Clinical Trials

Dr Jonathan Sheffield is Chief Executive of the National Institute for Health Research, Clinical Research Network (NIHR, CRN). This organisation is funded by the Department of Health to support the practical delivery of both academic and commercial clinical research in the NHS. It was responsible for recruiting over 600,000 patients into over 3,500 clinical studies last year.

Jonathan joins the Precision Medicine Catapult as a senior advisor on clinical trials, helping the organisation drive forward its plans to make UK the most attractive place in the world for the development and delivery of precision medicine.

He trained as a doctor at Dundee University, before following a career as a histopathologist at Yeovil District Hospital, where he was instrumental in developing its research capabilities. In 2003, he became Medical Director for the Trust, before moving onto University Hospitals Bristol – again as Medical Director.

In 2009, Jonathan was awarded an OBE for services to the NHS. Two years later, he was elected an Honorary Fellow of the Royal College of Physicians’ Faculty of Pharmaceutical Medicine – its highest honour – for his contribution in the area of clinical research delivery.

A passionate advocate for clinical research, Jonathan’s ambition is for participation in a suitable research study to be a standard treatment option, open to all NHS patients.

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